Therapeutic properties of some Nigerian higher fungi

Abstract

The therapeutic effects of some higher fungi – Fomes lignosus, Lentinus subnudus, Termitomyces robustus, Pleurotus tuber-regium, Pleurotus pulmonarius and their blend (mixture extract) against some pathogenic bacteria infected in albino rats (Rattus norvegicus) were studied. The bacteria used include E. coli, S. aureus, Salmonella typhi, P. aeruginosa, Streptococcus feacalis, and B. subtilis suspension of 0.1mlcfu intraperitoneally administered 7 days pre-fungi extract administration. Survival rates of the experimental rats were discovered to increase significantly. P. tuber-regium had the best therapeutic effect against the test bacteria.The pathological changes observed on the liver and kidney tissues from histological studies were reversed while they reduced to mild conditions in some. Undoubtedly, extracts from the studied fungi have therapeutic abilities against the test organisms.