ir.bowen.edu.ng:8181/jspui/handle/123456789/358 These are articles published in journals by academics staff 2026-04-22T00:07:50Z ir.bowen.edu.ng:8181/jspui/handle/123456789/2847 Title: Crystal structure of tricarbon­yltris(pyri­dine-κN)rhenium(I) tetra­fluorido­borate Authors: Ikotun, A. A.; Coogan, M. P.; Owoseni, A. A.; Bhuvanesh, N.; Egharevba, G. O. Abstract: In the title compound, [Re(C6H5N)3(CO)3]BF4, the Re1 ion is six-coordinated by three pyridine N atoms and three carbonyl C atoms. In each case, the carbonyl C atom lies trans to a pyridine N atom. In the crystal, the ions are linked via C—H F hydrogen bonds and C—H π interactions, forming a three-dimensional framework. The F atoms of the BF4 anion are disordered over two positions and gave a final refined occupancy ratio of 0.705 (11):0.295 (11). 2015-01-01T00:00:00Z ir.bowen.edu.ng:8181/jspui/handle/123456789/2846 Title: Phytochemistry and antimicrobial studies of African black soap and its modified samples Authors: Ikotun, A. A.; Olalere, C. A.; Adekunle, D. O.; Dawodu, M. O. Abstract: African black soap was prepared from palm kernel oil and the filtrate of cocoa pod ash. This was divided into five portions with different natural beauty enhancing organic compounds added to four portions. These samples were analyzed chemically by pH determinations, Infrared spectra analyses and phytochemical screenings. They were also screened for in vitro antibacterial activities against two Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) and two Gram-negative bacteria (Pseudomonas aeruginosa and Escherichia coli). Their pH values were between 8.90 and 9.78. Infrared spectra analyses of the black soap revealed strong bands due to υ (C=O) frequency of the keto group at 1668 and 1560 cm-1 and a strong band at 1379 cm-1 due to υ (C-O) frequency of the ester oxygen. The spectra of the modified samples showed no complexation via these oxygen donor atoms. Phytochemical screenings revealed the presence of saponins, flavonoids and terpenoids in the black soap. Modifying black soap by adding aleovera, camwood, lime, honey or shea butter eliminated one or two of its phytochemical components, but even facilitated its activities against some of the tested Gram-negative and Gram-positive bacteria. 2017-01-01T00:00:00Z ir.bowen.edu.ng:8181/jspui/handle/123456789/2843 Title: The African black soap from Elaeis guineensis (Palm kernel oil) and Theobroma cacao (Cocoa) and its transition metal complexes Authors: Ikotun, A. A.; Awosika, O. O.; Oladipo, M. A. Abstract: African black soap is an indigenous African organic soap formed by esterification. This was prepared by reacting palm kernel oil and the filtrate of cocoa pod ash. Chemical analyses revealed the moisture content was 26% (w/w), total fatty matter (TFM) was 44.75% (w/w), total fatty alkaline (TFA) was 0.22% (w/w), total alkaline (TA) was 11.78% (w/w) and pH was 10. The metal complexes were formed by the reaction of the synthesized black soap with some transition metal salts which included Cu(CH3COO)2.H2O, Pb(CH3COO)2.3H2O and FeCl3. The metal:ligand ratio, that is, M:L = 3:1, while the reaction was carried out in an aqueous medium to afford [Pb(C11H23COO-K+)2(C11H23COO-)2].9H2O, [Cu(BL)4(C11H23COO-)2].4H2O and [Fe(BL)2(C11H23COO-)Cl2] with the percentage yield of 56, 48 and 41%, respectively. Characterization of the black soap and complexes was done by spectroscopic analyses and determination of physicochemical properties. The solubility of the metal complexes was determined at room temperature in various solvents. Results showed that solubility increased as polarity decreased and it was most effective with non-polar organic solvents. Potassium ester (C11H23COO-K+), commonly called African black soap, has acted either as a monodentate or bidentate ligand forming metal complexes by coordinating through one or two of its oxygen donor atoms and also by entirely replacing the potassium ion with the transition metal (displacement reaction). Spectra analyses corroborate an octahedral structure for the Pb(II), a distorted octahedral structure for the Cu(II) and an octahedral Fe(III) complex. 2017-01-01T00:00:00Z ir.bowen.edu.ng:8181/jspui/handle/123456789/2842 Title: Design, synthesis, physicochemical and antimicrobial properties of rhenium(I) tricarbonyl complexes of 3-(phenylimino)indole-2-one Authors: Ikotun, A. A.; Coogan, M. P.; Owoseni, A. A.; Egharevba, G. O. Abstract: Modern medical application of luminescent d6 transition metal complexes to cell imaging has aroused great interest. Using the method of Coogan and co-workers, with slight modifications, the reactions of the Schiff base of isatin and aniline (L1; C14H10N2O; 41%) with Re(CO)5X (X = Cl; a and Br; b) in toluene yielded the complexes [Re(C14H10N2O)(CO)3X] (2a, 2b; 96% and 90% respectively). Refluxing in dry toluene under nitrogen and recrystallization afforded 2bcrystallizing as a solvate compound [Re(C14H10N2O)(CO)3Br].C2H5OH (3; 72%) in ethanol. The reaction of Complex 2b with AgBF4 in diethyl ether under nitrogen yielded [Re(C14H10N2O)(C4H10O)(CO)3]+BF4- (4). Characterization was done by Fourier Transform Infra-red Spectroscopy (FTIR), Electronic spectra, Magnetic susceptibility measurements and melting point determinations. The NMR and Mass Spectra analyses were also done for L1 and 2a. In-vitro antimicrobial studies was done using three gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis and haemolytic Staphylococcus aureus), three gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli and Klebsiella sp.) and three fungi (Aspergillus niger, Trichoderma viride and Penicillium citrinum). Complex 2a showed a broad-spectrum activity, 2b had activities against all gram-negative bacteria (and it was the most active against Pseudomonas aeruginosa) and 2c was active against all tested gram-positive bacteria. Complex 2b had the minimum inhibitory concentration (MIC) value of 1.25 μg/mL against Pseudomonas aeruginosa. The tested complexes showed selective activities in a distinct manner from the ligand and mostly with higher zones of inhibition against the tested organisms than tetracycline (standard clinical antibiotic) against the tested bacteria. All compounds were inactive against the tested fungi. 2019-01-01T00:00:00Z